Project Overview
The Computational Biology Program assembled Australia’s largest pediatric computational biology team to establish a robust data analysis and interpretation platform, vital for advancing precision medicine within our hospitals.
This program successfully pinpointed novel genes and markers associated with childhood cancer risk, translating these findings into enhanced diagnostic and treatment outcomes for children. With advanced technologies and close collaboration with clinicians, we managed to identify the genetic roots of cancer in over 90% of cases. These insights have not only informed new initiatives for disease prevention and early diagnosis in the wider community but have also extended into areas beyond pediatrics, including adult cancer and other rare diseases.
Ultimately, this investment has led to world-class healthcare for children and families in New South Wales, providing improved access to timely and tailored treatments.
Collaborations
- Children’s Cancer Institute (Australia)
- Kids Cancer Centre Sydney Children’s Hospital, Randwick, Sydney Children’s Hospitals Network (Australia)
- Zero Childhood Cancer national and international partners network (8 hospitals, 20 research institutes), including all three NSW Paediatric oncology centres, Peter MacCallum Cancer Centre, Murdoch Children’s Research Institute, Garvan Institute of Medical Research, ProCan Proteomics, Children’s Medical Research Institute (Australia)
- Children’s Hospital Westmead, Sydney Children’s Hospitals Network (Australia)
- Children’s Medical Research Institute (Australia)
- University of NSW (Australia)
- Sydney University (Australia)
- Children’s Hospital of Philadelphia (USA)
- Australian Bioinformatics Data Commons (Australia)
- Sick Kids, Toronto (Canada)
- Hartwig Medical Foundation (Australia, Netherlands)