Economic Impact and Framework for Precision Therapy - Cancer
Precision medicine is at the frontier of modern medical science – but it is expensive and challenging to introduce into the health system.
While we know it brings health benefits for many children, the long-term costs or effects on the health system are less clear.
Luminesce Alliance funding has supported research that will contribute to answering these questions.
In collaboration with the Australian Institute of Health Innovation (AIHI) at Macquarie University, implementation scientists and health economists studied ZERO to see how the research and healthcare staff who deliver the program interact and communicate.
By watching how relationships change and develop over time, the researchers can advise on what needs to be improved to support the smooth rollout of the program and remove barriers.
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We evaluated the implementation and costs of precision medicine through the Zero Childhood Cancer Program (ZERO). This work aimed to show the cost-effectiveness of a precision medicine program as a new model of care, and shed new light on the barriers and enablers in the delivery of a precision medicine program of this scale. Our health economics and implementation science approaches were the first of their kind in precision medicine for children’s cancer in Australia.
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Lead Investigators
- A/Professor Vanessa Tyrrell
Program Leader, Zero Childhood Cancer Co-Head of Theme, Personalised Medicine, Children’s Cancer Institute - A/Professor Tracey O’Brien
[Past] Director, Kids Cancer Centre, Sydney Children’s Hospital at Randwick
Research Team
- Professor Deborah Schofield, Director GenIMPACT: Centre for Economic Impacts of Genomic Medicine and Professor and Chair of Health Economics, Macquarie University
- Professor Jeffrey Braithwaite, Australian Institute of Health and Innovation, Macquarie University
- A/Professor Vanessa Tyrrell
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- Children’s Cancer Institute (Australia)
- Kids Cancer Centre, Sydney Children’s Hospitals Network, Sydney Children’s Hospital, Randwick (Australia)
- The Children’s Hospital Westmead, Sydney Children’s Hospitals Network (Australia)
- Zero Childhood Cancer national and international partners network (8 hospitals, 20 research institutes), incl. all three NSW Paediatric oncology centres, Children’s Hospital Westmead, Sydney Children’s Hospitals Network, John Hunter Children’s Hospital, and Sydney Children’s Hospital, Randwick (Australia)
- School of Women’s and Children’s Health, UNSW Sydney (Australia)
- Australian Institute for Health and Innovation, Macquarie University (Australia)
- GenIMPACT: Centre for Economic Impacts of Genomic Medicine, Macquarie University (Australia)
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Publications
See Luminesce Alliance Publications – completed research – Economic Impact and Framework for Sustainable Implementation of Paediatric Precision Medicine in the Australian Health System (cancer)
Articles:
Economic impact and health implementation analysis of a model for cancer